Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells
Background: Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder with a high prevalence, especially in industrialized countries.Dysbiosis of the intestinal microbiota has been observed in RA patients.For instance, new-onset untreated RA (NORA) is associated with the underrepresentation of the Clostridium cluster XIVa, including L