MICROBIOTA-DERIVED BUTYRATE LIMITS THE AUTOIMMUNE RESPONSE BY PROMOTING THE DIFFERENTIATION OF FOLLICULAR REGULATORY T CELLS

Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells

Background: Rheumatoid arthritis (RA) is a chronic debilitating autoimmune disorder with a high prevalence, especially in industrialized countries.Dysbiosis of the intestinal microbiota has been observed in RA patients.For instance, new-onset untreated RA (NORA) is associated with the underrepresentation of the Clostridium cluster XIVa, including L

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Laws of computing power in the computing power era

From the perspective of the growing demand for computing power, it was pointed out that the construction of ubiquitous, green, trusty, intelligent and agile computing power facilities was an inevitable choice for enterprises, regions and countries.The digital information infrastructure with the core of computing power will directly affect the devel

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